Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516084 | 0.85 | IDH1 (0.46) | ALDH1A1MEN1KMT2ALMNAIDH1 | |
| SCHEMBL11514550 | 0.84 | IDH1 (0.46) | ALDH1A1MEN1KMT2ALMNAIDH1 | |
| SCHEMBL11262145 | 0.84 | IDH1 (0.46) | MEN1KMT2ALMNAIDH1CYP1A2 | |
| SCHEMBL11514770 | 0.84 | IDH1 (0.46) | MAPTALDH1A1KMT2ALMNAIDH1 | |
| SCHEMBL11514005 | 0.84 | IDH1 (0.46) | MAPTMEN1KMT2ALMNAIDH1 | |
| SCHEMBL11512279 | 0.83 | IDH1 (0.45) | MAPTMEN1KMT2ALMNAIDH1 | |
| SCHEMBL11514708 | 0.82 | IDH1 (0.44) | MAPTKMT2ALMNAIDH1POLB | |
| SCHEMBL11516273 | 0.82 | IDH1 (0.53) | KMT2ALMNAIDH1POLB | |
| SCHEMBL11513595 | 0.81 | IDH1 (0.44) | MAPTKMT2ALMNAIDH1CYP1A2 | |
| SCHEMBL10427630 | 0.80 | MAPK1 (0.61) | MAPTALDH1A1MEN1KMT2AIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335249-A | PREEMERGENCE AND POSTEMERGENCE | ROHM AND HAAS COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4178169-A | Diphenyl sulfide, sulfoxide and sulfone plant growth regulators | ROHM AND HAAS COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4070178-A | Herbicidal diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1978-01-24 | — | — | US | disclosed |