Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516084 | 0.88 | IDH1 (0.46) | IDH1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL11514708 | 0.88 | IDH1 (0.44) | IDH1KMT2ALMNAL3MBTL1MAPT | |
| SCHEMBL11514550 | 0.87 | IDH1 (0.46) | IDH1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL11262145 | 0.87 | IDH1 (0.46) | IDH1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL11512279 | 0.86 | IDH1 (0.45) | IDH1KMT2ALMNAL3MBTL1MAPT | |
| SCHEMBL11516273 | 0.85 | IDH1 (0.53) | IDH1KMT2ALMNAL3MBTL1POLB | |
| SCHEMBL11514005 | 0.85 | IDH1 (0.46) | IDH1KMT2ALMNAL3MBTL1MAPT | |
| SCHEMBL11513595 | 0.85 | IDH1 (0.44) | IDH1KMT2ALMNAL3MBTL1MAPT | |
| SCHEMBL11258639 | 0.84 | MAPT (0.48) | IDH1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL11516087 | 0.82 | IDH1 (0.48) | IDH1KMT2ALMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178169-A | Diphenyl sulfide, sulfoxide and sulfone plant growth regulators | ROHM AND HAAS COMPANY (US) | 1979-12-11 | — | — | US | disclosed |