Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513004 | 0.86 | MAOB (0.67) | MAOBALDH1A1USP2TSHRCYP3A4 | |
| SCHEMBL30643087 | 0.81 | MAOB (0.64) | MAOBALDH1A1USP2TSHRCYP3A4 | |
| SCHEMBL11268699 | 0.81 | PTPN1 (0.55) | MAOBALDH1A1USP2TSHRMAOA | |
| SCHEMBL11262569 | 0.81 | PTPN1 (0.55) | MAOBALDH1A1MAOAMAPTNPC1 | |
| SCHEMBL11260734 | 0.81 | MAOB (0.64) | MAOBALDH1A1TSHRMAOAMAPT | |
| Hydrochloric Acid SCHEMBL11271928 | 0.80 | PTPN1 (0.54) | MAOBALDH1A1USP2TSHRMAOA | |
| SCHEMBL10898831 | 0.77 | MAOB (0.56) | MAOBALDH1A1USP2TSHRCYP3A4 | |
| SCHEMBL30649150 | 0.77 | ALDH1A1 (0.59) | MAOBALDH1A1USP2TSHRCYP3A4 | |
| SCHEMBL11253212 | 0.77 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL29933496 | 0.77 | MAOB (0.56) | MAOBALDH1A1USP2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320133-A | Penicillins and their antibacterial use | SANDOZ LTD. (CH) | 1982-03-16 | — | — | US | disclosed |