Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898831 | 1.00 | MAOB (0.56) | MAOBNPC1KMT2AALDH1A1USP2 | |
| SCHEMBL11513004 | 0.88 | MAOB (0.67) | MAOBNPC1KMT2AALDH1A1USP2 | |
| SCHEMBL11258849 | 0.87 | MAOB (0.51) | MAOBNPC1KMT2AALDH1A1USP2 | |
| SCHEMBL18530849 | 0.86 | SMN1; SMN2 (0.59) | MAOBNPC1KMT2AALDH1A1USP2 | |
| SCHEMBL29933509 | 0.86 | SMN1; SMN2 (0.59) | MAOBNPC1KMT2AALDH1A1USP2 | |
| SCHEMBL21083378 | 0.84 | NPC1 (0.54) | MAOBNPC1KMT2AALDH1A1USP2 | |
| SCHEMBL10899013 | 0.81 | MAOB (0.55) | MAOBNPC1KMT2AALDH1A1USP2 | |
| SCHEMBL29630236 | 0.80 | SIRT1 (0.66) | MAOBNPC1KMT2AALDH1A1TSHR | |
| SCHEMBL3377499 | 0.80 | SIRT1 (0.66) | MAOBNPC1KMT2AALDH1A1TSHR | |
| SCHEMBL6614160 | 0.79 | KDM4E (0.52) | MAOBNPC1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |