Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285257 | 0.89 | KMT2A (0.46) | TRPV1KMT2ALMNACTSDBACE1 | |
| SCHEMBL11252670 | 0.87 | TRPV1 (0.46) | TRPV1KMT2ALMNAMAOAMAOB | |
| SCHEMBL11245567 | 0.87 | BACE1 (0.45) | TRPV1KDM1AKMT2AMEN1LMNA | |
| SCHEMBL11253779 | 0.87 | SMPD1 (0.43) | TRPV1KDM1AKMT2ALMNACTSD | |
| SCHEMBL11245449 | 0.86 | TRPV1 (0.45) | TRPV1KMT2ALMNACTSDBACE1 | |
| SCHEMBL11245385 | 0.85 | ALDH1A1 (0.44) | KDM1AKMT2AMEN1LMNAMAOA | |
| SCHEMBL11249928 | 0.85 | TRPV1 (0.44) | TRPV1KMT2ALMNATSHRCTSD | |
| SCHEMBL11261454 | 0.84 | TRPV1 (0.44) | TRPV1KDM1AKMT2ACTSDBACE1 | |
| SCHEMBL11243369 | 0.84 | OPRD1 (0.45) | TRPV1KDM1AKMT2AMEN1TP53 | |
| SCHEMBL11474807 | 0.83 | IDO1 (0.41) | TRPV1KDM1AKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001428-B1 | INSECTICIDAL AND ACARICIDAL AGENTS CONTAINING CHROMAN DERIVATIVES, THEIR PREPARATION AND THEIR USE, AS WELL AS CHROMAN DERIVATIVES AND THEIR PREPARATION | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |