Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683435 | 0.84 | HTT (0.50) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3502859 | 0.83 | DNM1 (0.48) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL4580487 | 0.83 | DNM1 (0.48) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL27629301 | 0.83 | DNM1 (0.48) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9422919 | 0.82 | MEN1 (0.35) | LPAR1LPAR3LPAR2LPAR6LPAR4 | |
| SCHEMBL24083149 | 0.81 | HTT (0.45) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL15159038 | 0.81 | HTT (0.45) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL15160848 | 0.81 | DNM1 (0.45) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL723665 | 0.79 | HTT (0.41) | LPAR1LPAR3LPAR2HTTMEN1 | |
| SCHEMBL9422997 | 0.78 | TSHR (0.36) | LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012622-B1 | 1-TOSLOXY-2,2-ETHYLENEDIOXY-6,10-DIMETHYL UNDECANES AND UNDECENES, PROCESS FOR THE PREPARATION OF 2S*,3R*-3-BENZYLOXY-6,6-ETHYLENE DIOXY-2-METHYL-2-(5'-HYDROXY-4'-METHYLPENTYL)-OXEPANE, AND USE OF THE LATTER FOR THE PREPARATION OF OXEPAN-3-OL DERIVATIVES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-12-15 | — | — | EP | disclosed |