Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31566138 | 0.67 | LMNA (0.47) | ALDH1A1GAANPSR1POLBHPGD | |
| SCHEMBL18485449 | 0.67 | CES1 (0.47) | ALDH1A1ELANECES1NPSR1POLB | |
| SCHEMBL24439270 | 0.65 | ALDH1A1 (0.51) | ALDH1A1GAANPSR1POLBSRC | |
| SCHEMBL24439038 | 0.65 | ALDH1A1 (0.47) | ALDH1A1GAANPSR1POLBHSD17B10 | |
| SCHEMBL11267711 | 0.64 | ALDH1A1 (0.58) | ALDH1A1GAANPSR1POLBTSHR | |
| SCHEMBL11153369 | 0.63 | ALDH1A1 (0.37) | ALDH1A1ELANEGAANPSR1POLB | |
| SCHEMBL8178094 | 0.62 | CES1 (0.43) | ELANECES1POLBTSHRCES2 | |
| SCHEMBL8777494 | 0.62 | TDP1 (0.68) | ALDH1A1GAANPSR1POLBTDP1 | |
| SCHEMBL5058935 | 0.61 | CES1 (0.68) | ALDH1A1ELANEGAACES1HPGD | |
| SCHEMBL6627600 | 0.61 | CES1 (0.39) | ALDH1A1ELANECES1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010441-B1 | THE USE OF SYMMETRICALLY SUBSTITUTED PYROMELLITIC DIIMIDES AS RUMINANT FEED ADDITIVES. COMPOSITIONS CONTAINING THESE FEED ADDITIVES | MERCK & CO. INC. (US) | 1982-04-21 | — | — | EP | disclosed |
| US-4212880-A | INCREASE FEED EFFICIENCY | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0010441-A1 | The use of symmetrically substituted pyromellitic diimides as ruminant feed additives. Compositions containing these feed additives | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | disclosed |