Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108753 | 0.92 | ALDH1A1 (0.42) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11257131 | 0.90 | TP53 (0.43) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11261872 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11602820 | 0.85 | RAB9A (0.41) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11254670 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11271793 | 0.83 | PLCG1 (0.42) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11635857 | 0.82 | TP53 (0.41) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10743182 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10402450 | 0.82 | ELANE (0.40) | ALDH1A1GAA | |
| SCHEMBL9443869 | 0.82 | TP53 (0.40) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364865-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| US-4070477-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |