Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 5/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256987 | 0.78 | USP7 (0.45) | MEN1KMT2AABL1VRK1RPS6KA3 | |
| SCHEMBL11262307 | 0.78 | CYP2A6 (0.44) | ALDH1A1HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL11252904 | 0.75 | MAPT (0.49) | ALDH1A1ALOX15HSD17B10MAPTHTT | |
| SCHEMBL27017934 | 0.72 | KDM4E (0.41) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL13562426 | 0.71 | FYN (0.46) | ABL1FYNVRK1 | |
| SCHEMBL29879420 | 0.71 | ALDH1A1 (0.68) | ALDH1A1ALOX15HSD17B10GAAMEN1 | |
| SCHEMBL11267771 | 0.71 | ABL1 (0.58) | ALDH1A1ALOX15HSD17B10GAAMEN1 | |
| SCHEMBL13562437 | 0.71 | MKNK1 (0.60) | ABL1FYNCHEK2 | |
| SCHEMBL18648263 | 0.70 | ALDH1A1 (0.55) | ALDH1A1ALOX15HSD17B10GAAMEN1 | |
| SCHEMBL15730886 | 0.70 | ABL1 (0.44) | ABL1VRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366319-A | Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones | STERLING DRUG INC. (US) | 1982-12-28 | — | — | US | disclosed |
| US-4310531-A | 5-(Pyridinyl)-benzoxazol-2(3H)-ones and their use as cardiotonics | STERLING DRUG INC. (US) | 1982-01-12 | — | — | US | disclosed |