Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 6/20 | 0.45 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660459 | 0.83 | DYRK1A (0.46) | USP7VRK1RPS6KA3MEN1KMT2A | |
| SCHEMBL13562426 | 0.81 | FYN (0.46) | VRK1ABL1CCR1CCR5CCR8 | |
| SCHEMBL624413 | 0.81 | USP7 (0.69) | USP7 | |
| SCHEMBL11262307 | 0.81 | CYP2A6 (0.44) | VRK1ABL1CCR1CCR5CCR8 | |
| SCHEMBL10105111 | 0.80 | PSMB5 (0.49) | ABL1CCR1CCR5CCR8MEN1 | |
| SCHEMBL11259631 | 0.78 | ALDH1A1 (0.47) | VRK1ABL1RPS6KA3MEN1KMT2A | |
| SCHEMBL13562437 | 0.78 | MKNK1 (0.60) | ABL1 | |
| SCHEMBL16194268 | 0.77 | FYN (0.39) | USP7ABL1CLK1DYRK1ADYRK2 | |
| SCHEMBL15257349 | 0.75 | PTGS2 (0.60) | — | |
| SCHEMBL13562427 | 0.75 | RPS6KA3 (0.49) | USP7ABL1RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366319-A | Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones | STERLING DRUG INC. (US) | 1982-12-28 | — | — | US | disclosed |
| US-4310531-A | 5-(Pyridinyl)-benzoxazol-2(3H)-ones and their use as cardiotonics | STERLING DRUG INC. (US) | 1982-01-12 | — | — | US | disclosed |