Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266222 | 0.88 | GAA (0.48) | GAAALDH1A1ALOX15MAPK1PPARA | |
| SCHEMBL11255435 | 0.87 | GAA (0.46) | GAAALDH1A1ALOX15MAPK1PPARA | |
| SCHEMBL11259318 | 0.87 | GAA (0.42) | GAAALDH1A1ALOX15MAPK1PPARA | |
| SCHEMBL11267432 | 0.86 | GAA (0.45) | GAAALDH1A1ALOX15MAPK1PPARA | |
| SCHEMBL11261797 | 0.80 | PPARA (0.43) | GAAALDH1A1MAPK1PPARAABCB11 | |
| SCHEMBL11264489 | 0.80 | GAA (0.42) | GAAALDH1A1ALOX15MAPK1PPARA | |
| SCHEMBL11260420 | 0.74 | GAA (0.39) | GAAALDH1A1ALOX15MAPK1PPARA | |
| SCHEMBL11263577 | 0.74 | GAA (0.47) | GAAALDH1A1ALOX15MAPK1TSHR | |
| SCHEMBL11269896 | 0.73 | GAA (0.38) | GAAALDH1A1ALOX15MAPK1PPARA | |
| SCHEMBL11269891 | 0.73 | HTR6 (0.38) | GAAALDH1A1ALOX15MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |