SCHEMBL11259660

SCHEMBL11259660

CCCCCCCCCCC(N)c1ccco1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.44
CSNK1E P49674 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
OPRM1 P35372 1/20 0.38
CA2 P00918 1/20 0.37
SPHK1 Q9NYA1 2/20 0.36
GAA P10253 1/20 0.35
CYP2D6 P10635 2/20 0.34
KCNH2 Q12809 1/20 0.34
PLA2G1B P04054 1/20 0.34
PLA2G2A P14555 1/20 0.34
GMNN O75496 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
THPO P40225 1/20 0.34
MTOR P42345 1/20 0.34
BLM P54132 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10754424 1.00 SLC2A1 (0.44) SLC2A1CSNK1EMEN1KMT2AOPRM1
SCHEMBL13479612 0.93 ALDH1A1 (0.37) SLC2A1MEN1KMT2ACA2GAA
SCHEMBL8159767 0.85 MEN1 (0.41) SLC2A1CSNK1EMEN1KMT2AOPRM1
SCHEMBL18934219 0.85 MEN1 (0.41) SLC2A1CSNK1EMEN1KMT2AOPRM1
SCHEMBL30264728 0.81 KMT2A (0.42) CSNK1EMEN1KMT2AGAAPOLB
SCHEMBL11077246 0.81 ALOX5 (0.34) MEN1KMT2AKDM4E
SCHEMBL12261798 0.81
SCHEMBL12261901 0.81
SCHEMBL12261820 0.81
SCHEMBL5613043 0.80 KMT2A (0.52) CSNK1EMEN1KMT2ASPHK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4357476-A Nonylamines CIBA GEIGY CORPORATION, N.Y. (US) 1982-11-02 US disclosed
US-4139560-A Nonylamines CIBA GEIGY CORPORATION (US) 1979-02-13 US disclosed