Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263417 | 0.99 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDKDM4EALDH1A1NPY1R | |
| SCHEMBL11268609 | 0.92 | MAPT (0.35) | SMN1; SMN2HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL11266953 | 0.91 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDMAPTTP53LMNA | |
| SCHEMBL11261972 | 0.91 | TP53 (0.35) | SMN1; SMN2HPGDMAPTTP53LMNA | |
| SCHEMBL11255511 | 0.91 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDALDH1A1MAPTTP53 | |
| SCHEMBL11271896 | 0.89 | TP53 (0.38) | SMN1; SMN2HPGDMAPTTP53LMNA | |
| SCHEMBL11260654 | 0.88 | HPGD (0.33) | SMN1; SMN2HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL11261658 | 0.88 | TP53 (0.37) | SMN1; SMN2MAPTTP53LMNATSHR | |
| SCHEMBL11271775 | 0.88 | TP53 (0.37) | SMN1; SMN2MAPTTP53LMNATSHR | |
| SCHEMBL11265476 | 0.87 | TP53 (0.38) | SMN1; SMN2HPGDMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |