Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266953 | 0.99 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTTP53CNR2ESR1 | |
| SCHEMBL11263417 | 0.92 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTTP53HPGDLMNA | |
| SCHEMBL11261972 | 0.91 | TP53 (0.35) | SMN1; SMN2MAPTTP53CNR2ESR1 | |
| SCHEMBL11259692 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTTP53HPGDLMNA | |
| SCHEMBL11268609 | 0.90 | MAPT (0.35) | SMN1; SMN2MAPTTP53CNR2ESR1 | |
| SCHEMBL11261658 | 0.90 | TP53 (0.37) | SMN1; SMN2MAPTTP53CNR2ESR1 | |
| SCHEMBL11271775 | 0.90 | TP53 (0.37) | SMN1; SMN2MAPTTP53CNR2ESR1 | |
| SCHEMBL11271896 | 0.89 | TP53 (0.38) | SMN1; SMN2MAPTTP53CNR2ESR1 | |
| SCHEMBL11265476 | 0.87 | TP53 (0.38) | SMN1; SMN2MAPTTP53ESR1MEN1 | |
| SCHEMBL11264372 | 0.87 | DRD2 (0.34) | SMN1; SMN2MAPTTP53ESR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |