Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271775 | 0.99 | TP53 (0.37) | TP53SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL11261658 | 0.99 | TP53 (0.37) | TP53SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL11265476 | 0.98 | TP53 (0.38) | TP53SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL11266928 | 0.97 | TSHR (0.36) | TP53SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL11271322 | 0.94 | TSHR (0.41) | TP53SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL11268609 | 0.92 | MAPT (0.35) | TP53SMN1; SMN2MAPTLMNAESR1 | |
| SCHEMBL11261972 | 0.91 | TP53 (0.35) | TP53SMN1; SMN2MAPTLMNAESR1 | |
| SCHEMBL11266953 | 0.90 | SMN1; SMN2 (0.36) | TP53SMN1; SMN2MAPTLMNAESR1 | |
| SCHEMBL11255511 | 0.89 | SMN1; SMN2 (0.36) | TP53SMN1; SMN2MAPTLMNAESR1 | |
| SCHEMBL11259692 | 0.89 | SMN1; SMN2 (0.37) | TP53SMN1; SMN2MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |