Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215621 | 0.85 | ACE (0.50) | ACEALDH1A1POLB | |
| SCHEMBL11272121 | 0.83 | ACE (0.43) | ACEPOLB | |
| SCHEMBL11268004 | 0.78 | ACE (0.53) | ACE | |
| SCHEMBL11263533 | 0.77 | ACE (0.39) | ACE | |
| SCHEMBL11271111 | 0.77 | ACE (0.68) | ACE | |
| SCHEMBL11305254 | 0.77 | ACE (0.68) | ACE | |
| SCHEMBL11272559 | 0.77 | ACE (0.39) | ACE | |
| SCHEMBL11263538 | 0.77 | ACE (0.39) | ACE | |
| SCHEMBL11168789 | 0.77 | ATM (0.44) | ACEPOLB | |
| SCHEMBL11273941 | 0.76 | ACE (0.43) | ACEPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330548-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-05-18 | — | — | US | disclosed |
| US-4296113-A | FOR TREATING HYPERTENSION BY INHIBITING ANGIOTENSIN CONVERTING ENZYME | E. R. SQUIBB & SONS, INC. (US) | 1981-10-20 | — | — | US | disclosed |