Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.47 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259703 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL10406165 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL10406164 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL1919347 | 0.80 | HTT (0.51) | ALDH1A1GAAMEN1KMT2AHSD17B10 | |
| SCHEMBL1919344 | 0.80 | HTT (0.51) | ALDH1A1GAAMEN1KMT2AHSD17B10 | |
| SCHEMBL3272288 | 0.80 | HTT (0.51) | ALDH1A1GAAMEN1KMT2AHSD17B10 | |
| SCHEMBL3479004 | 0.80 | HCAR2 (0.42) | ALDH1A1GAAHCAR2MEN1KMT2A | |
| SCHEMBL3479005 | 0.80 | HCAR2 (0.42) | ALDH1A1GAAHCAR2MEN1KMT2A | |
| SCHEMBL1289017 | 0.79 | KDM4E (0.56) | ALDH1A1GAAMEN1KMT2ARAB9A | |
| SCHEMBL8514348 | 0.79 | KDM4E (0.56) | ALDH1A1GAAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109881-A1 | Heteroaryl Compounds as Ligand Directed Degraders of IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-04 | — | — | US | disclosed |
| EP-0051084-A1 | Substituted 1H-1,2,4-triazoles | AMERICAN CYANAMID COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4329463-A | ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4259504-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109881-A1 | Heteroaryl Compounds as Ligand Directed Degraders of IRAK4 | IRAK4, IRAK2, IRAK3 | ALDH1A1 3457/4885GAA 2944/4885APP 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.