Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919344 | 1.00 | HTT (0.51) | HTTKMT2AKDM4ENAPRTHSD17B10 | |
| SCHEMBL3272288 | 1.00 | HTT (0.51) | HTTKMT2AKDM4ENAPRTHSD17B10 | |
| SCHEMBL1289020 | 0.81 | KDM4E (0.56) | HTTKMT2AKDM4ENAPRTPOLB | |
| SCHEMBL1289017 | 0.81 | KDM4E (0.56) | HTTKMT2AKDM4ENAPRTPOLB | |
| SCHEMBL21408786 | 0.81 | HCAR2 (0.47) | HTTKMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL21431824 | 0.81 | HCAR2 (0.47) | HTTKMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL11259703 | 0.80 | ALDH1A1 (0.49) | HTTKMT2AKDM4EHSD17B10LMNA | |
| SCHEMBL11259705 | 0.80 | ALDH1A1 (0.49) | HTTKMT2AKDM4EHSD17B10LMNA | |
| SCHEMBL4901313 | 0.79 | CYP1A2 (0.49) | HTTKMT2ALMNAPOLBL3MBTL1 | |
| SCHEMBL4901316 | 0.79 | CYP1A2 (0.49) | HTTKMT2ALMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220104493-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-07 | — | — | US | disclosed |
| EP-3920701-A1 | HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-12-15 | — | — | EP | disclosed |
| CN-113412055-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2021-09-17 | — | — | CN | disclosed |
| WO-2020161163-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| CN-104877001-B | Antifungal formulations | 西尼克斯公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-103159738-B | The heteroaryl aroma compounds of alkynyl bridging and application thereof | 上海泓博智源医药股份有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-102491969-B | Heteroaromatic quinoline compounds and the purposes as PDE10 inhibitor thereof | PFIZER PRODUCTS INC. (US) | 2015-08-19 | — | — | CN | disclosed |
| EP-2326172-B1 | ANTIFUNGAL AGENTS | SCYNEXIS INC (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2326172-B1 | ANTIFUNGAL AGENTS | SCYNEXIS INC (US) | 2014-10-22 | — | — | EP | disclosed |
| US-20130158031-A1 | ALKYNE-BRIDGED HETERO-AROMATICS AND USES THEREOF | SU ZHOU JING HONG BIOTECH CO., LTD. (CN) | 2013-06-20 | — | — | US | disclosed |
| WO-2010019203-A1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-7429665-B2 | Heteroaromatic quinoline compounds | PFIZER INC (US) | 2008-09-30 | — | — | US | disclosed |
| US-20080214607-A1 | HETEROAROMATIC QUINOLINE COMPOUNDS | PFIZER INC | 2008-09-04 | — | — | US | disclosed |
| CN-101098866-A | Heteroaromatic quinoline compounds and their use as pde10 inhibitors | PFIZER (US) | 2008-01-02 | — | — | CN | disclosed |
| EP-1841757-A2 | HETEROAROMATIC QUINOLINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS | Pfizer Products Incorporated (US) | 2007-10-10 | — | — | EP | disclosed |
| US-20060154931-A1 | Heteroaromatic quinoline compounds | PFIZER INC | 2006-07-13 | — | — | US | disclosed |
| WO-2006072828-A2 | HETEROAROMATIC QUINOLINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-07-13 | — | — | WO | disclosed |
| EP-0051084-A1 | Substituted 1H-1,2,4-triazoles | AMERICAN CYANAMID COMPANY (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4329463-A | ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4259504-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220104493-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | HTT 673/4885KMT2A 1038/4885KDM4E 1194/4885 |
| US-20060154931-A1 | Heteroaromatic quinoline compounds | PDE12, PDE7A, PDE4A | HTT 834/4885KMT2A 1251/4885KDM4E 1059/4885 |
| US-20130158031-A1 | ALKYNE-BRIDGED HETERO-AROMATICS AND USES THEREOF | CHRNA10, ATXN10, SCN10A | HTT 18/4885KMT2A 1162/4885KDM4E 784/4885 |
| US-20080214607-A1 | HETEROAROMATIC QUINOLINE COMPOUNDS | PDE12, PDE7A, PDE4A | HTT 834/4885KMT2A 1251/4885KDM4E 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.