Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255700 | 0.84 | MCL1 (0.33) | MCL1 | |
| SCHEMBL11249109 | 0.83 | — | — | |
| SCHEMBL11248598 | 0.82 | MCL1 (0.35) | MCL1 | |
| SCHEMBL11260318 | 0.81 | MAP2 (0.37) | — | |
| SCHEMBL11349249 | 0.81 | JAK2 (0.32) | MCL1 | |
| SCHEMBL11256811 | 0.81 | — | — | |
| SCHEMBL11252698 | 0.81 | ADORA2B (0.31) | — | |
| SCHEMBL11344946 | 0.80 | ALDH1A1 (0.43) | — | |
| SCHEMBL11255035 | 0.80 | CSF1R (0.34) | MCL1 | |
| SCHEMBL11251572 | 0.80 | MCL1 (0.32) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342769-A | 2-[(Methylsulfinyl)acetyl]-3-heterocyclicindoles and derivatives thereof as immunosuppressants | SCHERING CORPORATION (US) | 1982-08-03 | — | — | US | disclosed |
| US-4328345-A | Pyridyl substituted indoles | SCHERING CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |
| EP-0010617-B1 | NOVEL 2-SUBSTITUTED-3-HETEROCYCLYLINDOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1981-08-05 | — | — | EP | disclosed |
| US-4225711-A | Substituted 2-[(methylsulfinyl)acetyl]-3-heterocyclicindoles and their use as immunosuppressants | SCHERING CORPORATION (US) | 1980-09-30 | — | — | US | disclosed |
| EP-0010617-A1 | Novel 2-substituted-3-heterocyclylindoles, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1980-05-14 | — | — | EP | disclosed |