Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259843 | 1.00 | HPGD (0.62) | HPGDCYP1A2CYP2C19ALDH1A1NPSR1 | |
| SCHEMBL11259847 | 1.00 | HPGD (0.62) | HPGDCYP1A2CYP2C19ALDH1A1NPSR1 | |
| SCHEMBL30913220 | 0.84 | SLC6A19 (0.69) | HPGDCYP1A2CYP2C19ALDH1A1NPSR1 | |
| SCHEMBL29282139 | 0.84 | SLC6A19 (0.69) | HPGDCYP1A2CYP2C19ALDH1A1NPSR1 | |
| SCHEMBL11257542 | 0.83 | SLC6A19 (0.72) | HPGDALDH1A1NPSR1TRPV1SMN1; SMN2 | |
| SCHEMBL11257541 | 0.83 | SLC6A19 (0.72) | HPGDALDH1A1NPSR1TRPV1SMN1; SMN2 | |
| SCHEMBL11257545 | 0.83 | SLC6A19 (0.72) | HPGDALDH1A1NPSR1TRPV1SMN1; SMN2 | |
| N-Isobutylcinnamamide SCHEMBL11965211 | 0.82 | KMT2A (0.63) | HPGDCYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL16610377 | 0.80 | MEN1 (0.61) | HPGDNPSR1TRPV1SMN1; SMN2LMNA | |
| SCHEMBL15606032 | 0.80 | HPGD (0.64) | HPGDCYP1A2CYP2C19ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309444-A | ANTICONVULSANT CINNAMAMIDES | BURROUGHS WELLCOME CO. (US) | 1982-01-05 | — | — | US | claimed |
| WO-2014073994-A2 | NEW ALKANOLAMIDE DERIVATIVES OF CINNAMIC ACID AND USE OF ALKANOLAMIDE DERIVATIVES OF CINNAMIC ACID FOR PREPARATION OF DRUGS | UNIWERSYTET JAGIELLONSKI (PL) | 2014-05-15 | — | — | WO | disclosed |
| US-4309444-A | ANTICONVULSANT CINNAMAMIDES | BURROUGHS WELLCOME CO. (US) | 1982-01-05 | — | — | US | disclosed |