Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29282139 | 1.00 | SLC6A19 (0.69) | SLC6A19CYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL11259847 | 0.84 | HPGD (0.62) | SLC6A19CYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL11259843 | 0.84 | HPGD (0.62) | SLC6A19CYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL11259846 | 0.84 | HPGD (0.62) | SLC6A19CYP1A2HPGDCYP2C19ALDH1A1 | |
| SCHEMBL15549702 | 0.84 | HPGD (0.67) | CYP1A2HPGDCYP2C19ALDH1A1NPSR1 | |
| SCHEMBL15548332 | 0.84 | HPGD (0.67) | CYP1A2HPGDCYP2C19ALDH1A1NPSR1 | |
| SCHEMBL15606032 | 0.84 | HPGD (0.64) | CYP1A2HPGDCYP2C19ALDH1A1NPSR1 | |
| SCHEMBL8740837 | 0.83 | SLC6A19 (0.71) | SLC6A19MMP1MMP2MMP9 | |
| SCHEMBL8740836 | 0.83 | SLC6A19 (0.71) | SLC6A19MMP1MMP2MMP9 | |
| SCHEMBL8740838 | 0.83 | SLC6A19 (0.71) | SLC6A19MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986241-A | Biphenyl derivative, pharmaceutical composition and application thereof | 武汉睿健医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |