Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NEDD4 | P46934 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268644 | 0.80 | RXFP1 (0.42) | RXFP1TP53ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11252283 | 0.78 | KDM4E (0.42) | RXFP1TP53ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11264828 | 0.69 | ALDH1A1 (0.41) | RXFP1ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL27575155 | 0.66 | ALDH1A1 (0.54) | RXFP1TP53ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19001515 | 0.63 | ALDH1A1 (0.49) | RXFP1ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL11251471 | 0.62 | ALDH1A1 (0.41) | RXFP1TP53ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15219369 | 0.62 | ALDH1A1 (0.56) | RXFP1TP53ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21614331 | 0.61 | BCHE (0.64) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL649985 | 0.61 | NAAA (0.54) | ALDH1A1MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL11328179 | 0.61 | PDE10A (0.53) | RXFP1ALDH1A1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349674-A | Quinoalinyl esters of carbamimidothioic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |