Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270355 | 0.91 | TP53 (0.39) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11270366 | 0.91 | TP53 (0.39) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11267296 | 0.91 | TP53 (0.39) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11267307 | 0.91 | TP53 (0.39) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11271460 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11271464 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11255951 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11273906 | 0.89 | CASP1 (0.41) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11273911 | 0.89 | CASP1 (0.41) | ALDH1A1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11261926 | 0.88 | PTPN1 (0.42) | TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364865-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| US-4070477-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |