Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805249 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAGRIA1GRIA2 | |
| SCHEMBL29857764 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1GAATSHR | |
| SCHEMBL2757601 | 0.73 | KDM5B (0.38) | KDM4EALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL7378485 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL7381333 | 0.70 | KDM4E (0.37) | KDM4EALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL7381336 | 0.70 | KDM4E (0.37) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL7412862 | 0.69 | KDM4E (0.42) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL7383793 | 0.68 | GAA (0.37) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL5586517 | 0.68 | ALDH1A1 (0.43) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL23059087 | 0.66 | KDM4E (0.33) | KDM4EALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338434-A | ANTIBIOTICS AND ANIMAL FEED SUPPLEMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-07-06 | — | — | US | disclosed |
| EP-0000392-B1 | CEPHALOSPORINS AND PENICILLINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |
| US-4215118-A | BACTERICIDES, ANIMAL GROWTH PROMOTERS, PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-07-29 | — | — | US | disclosed |
| EP-0000392-A2 | Cephalosporins and penicillins, processes for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1979-01-24 | — | — | EP | disclosed |