Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805249 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL20592993 | 0.73 | ALDH1A1 (0.36) | ALDH1A1NPSR1KDM4EL3MBTL1GAA | |
| SCHEMBL8784515 | 0.71 | PDE4D (0.56) | ALDH1A1NPSR1KDM4EL3MBTL1GAA | |
| SCHEMBL3322964 | 0.69 | KDM4E (0.52) | ALDH1A1NPSR1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL7378485 | 0.68 | KDM4E (0.44) | ALDH1A1NPSR1KDM4EL3MBTL1GAA | |
| SCHEMBL7381336 | 0.67 | KDM4E (0.37) | ALDH1A1KDM4EGAASMN1; SMN2LMNA | |
| SCHEMBL7381333 | 0.67 | KDM4E (0.37) | ALDH1A1KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL19003644 | 0.67 | KDM4E (0.34) | ALDH1A1KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL7412862 | 0.67 | KDM4E (0.42) | ALDH1A1NPSR1KDM4EGAASMN1; SMN2 | |
| SCHEMBL2757601 | 0.66 | KDM5B (0.38) | ALDH1A1KDM4EGAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007526892-A | — | — | 2007-09-20 | — | — | JP | claimed |
| EP-1648898-A1 | HETARYL-SUBSTITUTED PYRAZOLIDINDIONE DERIVATIVES WITH PESTICIDAL CHARACTERISTICS | Bayer CropScience AG (DE) | 2006-04-26 | — | — | EP | claimed |
| WO-2005005428-A1 | HETARYL-SUBSTITUTED PYRAZOLIDINDIONE DERIVATIVES WITH PESTICIDAL CHARACTERISTICS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-1648898-A1 | HETARYL-SUBSTITUTED PYRAZOLIDINDIONE DERIVATIVES WITH PESTICIDAL CHARACTERISTICS | Bayer CropScience AG (DE) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005005428-A1 | HETARYL-SUBSTITUTED PYRAZOLIDINDIONE DERIVATIVES WITH PESTICIDAL CHARACTERISTICS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | WO | disclosed |