Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248894 | 0.87 | ALDH1A1 (0.54) | FFAR4ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL1430497 | 0.86 | PTGDR2 (0.43) | FFAR4MAPTGAAPTGDR2SMN1; SMN2 | |
| SCHEMBL1195159 | 0.82 | CYP2C9 (0.62) | ALDH1A1PTGDR2SMN1; SMN2P2RX7CYP1A2 | |
| SCHEMBL11247967 | 0.80 | CYP2C9 (0.56) | ALDH1A1MAPTGAAHTTPTGDR2 | |
| SCHEMBL1430458 | 0.79 | SMN1; SMN2 (0.49) | KDM4EGAAPTGDR2SMN1; SMN2P2RX7 | |
| SCHEMBL11247972 | 0.78 | PTGDR2 (0.47) | GAAPTGDR2SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL3833333 | 0.78 | CYP1A2 (0.50) | ALDH1A1MAPTKDM4EPTGDR2SMN1; SMN2 | |
| SCHEMBL11242627 | 0.77 | CYP1A2 (0.52) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL3862973 | 0.77 | PTGDR2 (0.43) | ALDH1A1MAPTKDM4EGAAPTGDR2 | |
| SCHEMBL27971496 | 0.76 | TSHR (0.43) | ALDH1A1MAPTKDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |