Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1195159 | 0.88 | CYP2C9 (0.62) | CYP1A2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL4156010 | 0.88 | MARS1 (0.44) | MYCWDR5PTGDR2SLC16A3SLC16A1 | |
| SCHEMBL4158179 | 0.88 | MEN1 (0.50) | CYP1A2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL3835898 | 0.86 | PTGDR2 (0.47) | NPC1RAB9AMYCWDR5GRM1 | |
| SCHEMBL11247967 | 0.83 | CYP2C9 (0.56) | CYP1A2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL3862973 | 0.82 | PTGDR2 (0.43) | CYP1A2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL1430497 | 0.82 | PTGDR2 (0.43) | CYP1A2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL11255264 | 0.81 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL11242627 | 0.80 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19NPC1RAB9A | |
| SCHEMBL11252577 | 0.80 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2106213-B1 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOL-4-YL-ACETIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDE AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2015-02-11 | — | — | EP | claimed |
| CN-101583276-B | Substituted 1- (3-pyridyl) -pyrazol-4-yl acetic acids, method for the production thereof, and use thereof as herbicides and plant growth regulators | BAYER CROPSCIENCE AG | 2013-08-28 | — | — | CN | claimed |
| EP-2106213-A2 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOLE-4-YL ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2009-10-07 | — | — | EP | claimed |
| US-20090036310-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic Acids, Processes for Their Preparation and Their Use as Herbicides and Plant Growth Regulators | BAYER CORPSCIENCE GMBH (DE) | 2009-02-05 | — | — | US | claimed |
| WO-2008080504-A2 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOLE-4-YL ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2008-07-10 | — | — | WO | claimed |
| EP-1938686-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-yl-acetic acids, process for their preparation and their use as herbicide and plant growth regulator. | Bayer CropScience AG (DE) | 2008-07-02 | — | — | EP | claimed |
| EP-2106213-B1 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOL-4-YL-ACETIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDE AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2015-02-11 | — | — | EP | disclosed |
| CN-101583276-B | Substituted 1- (3-pyridyl) -pyrazol-4-yl acetic acids, method for the production thereof, and use thereof as herbicides and plant growth regulators | BAYER CROPSCIENCE AG | 2013-08-28 | — | — | CN | disclosed |
| US-8252723-B2 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic acids, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2012-08-28 | — | — | US | disclosed |
| EP-2106213-A2 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOLE-4-YL ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2009-10-07 | — | — | EP | disclosed |
| US-20090036310-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic Acids, Processes for Their Preparation and Their Use as Herbicides and Plant Growth Regulators | BAYER CORPSCIENCE GMBH (DE) | 2009-02-05 | — | — | US | disclosed |
| WO-2008080504-A2 | SUBSTITUTED 1-(3-PYRIDINYL)PYRAZOLE-4-YL ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2008-07-10 | — | — | WO | disclosed |
| EP-1938686-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-yl-acetic acids, process for their preparation and their use as herbicide and plant growth regulator. | Bayer CropScience AG (DE) | 2008-07-02 | — | — | EP | disclosed |
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036310-A1 | Substituted 1-(3-pyridinyl)pyrazol-4-ylacetic Acids, Processes for Their Preparation and Their Use as Herbicides and Plant Growth Regulators | DDT, DDC, HPD | CYP1A2 185/4885CYP2C9 384/4885CYP2C19 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.