Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268122 | 0.83 | CES1 (0.40) | CES1PPOXHTR2AHTR2CHTR2B | |
| SCHEMBL454553 | 0.82 | PPOX (0.52) | CES1PPOXSIRT2HTR2AHTR2C | |
| SCHEMBL9148787 | 0.82 | CES1 (0.38) | CES1 | |
| SCHEMBL28641724 | 0.80 | CES1 (0.50) | CES1PPOXSIRT2HTR2AHTR2C | |
| SCHEMBL11260054 | 0.77 | CES1 (0.47) | CES1PARP1GSK3B | |
| SCHEMBL11222151 | 0.75 | CES1 (0.47) | CES1PPOX | |
| SCHEMBL11222720 | 0.71 | CES1 (0.41) | CES1PPOX | |
| SCHEMBL11226468 | 0.71 | CES1 (0.41) | CES1PPOX | |
| SCHEMBL29011346 | 0.69 | PPOX (0.52) | CES1PPOXPARP1PKMGSK3B | |
| SCHEMBL28721617 | 0.69 | ATM (0.47) | CES1PPOXPARP1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317929-A | Tetraphenylketazines and isoindolinone pigments obtained therefrom | CIBA-GEIGY CORPORATION (US) | 1982-03-02 | — | — | US | disclosed |
| US-4231931-A | YELLOW TO RED HUES | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |