Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 11/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.32 |
| ▸ | WEE1 | P30291 | 3/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 3/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13297043 | 0.83 | CES1 (0.39) | CES1 | |
| SCHEMBL895684 | 0.83 | CES1 (0.56) | CES1DNMT1PPOXRETGRK5 | |
| SCHEMBL11527215 | 0.77 | MAPK1 (0.40) | CES1NSD2 | |
| SCHEMBL11222720 | 0.77 | CES1 (0.41) | CES1DNMT1PPOXCHEK1WEE1 | |
| SCHEMBL11226468 | 0.77 | CES1 (0.41) | CES1DNMT1PPOXCHEK1WEE1 | |
| SCHEMBL11260122 | 0.75 | CES1 (0.47) | CES1PPOX | |
| SCHEMBL11259415 | 0.75 | CES1 (0.47) | CES1RETGRK5TYRO3DYRK1B | |
| SCHEMBL11260054 | 0.75 | CES1 (0.47) | CES1RETGRK5TYRO3DYRK1B | |
| SCHEMBL18663500 | 0.73 | CES1 (0.46) | CES1 | |
| SCHEMBL3143690 | 0.71 | UCHL1 (0.35) | CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723882-B2 | Black isoindolinone pigment and coloring agent | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2020-07-28 | — | — | US | disclosed |
| US-4318850-A | Carboxamide type azomethine pigment | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-03-09 | — | — | US | disclosed |
| US-4239686-A | Process for producing phthalimido derivatives | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723882-B2 | Black isoindolinone pigment and coloring agent | IK, NDUFS8, NDUFA8 | CES1 4348/4885DNMT1 624/4885PPOX 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.