Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579468 | 0.95 | NAAA (0.51) | HTTTSHRKDM4ENAAASMN1; SMN2 | |
| SCHEMBL8747369 | 0.94 | NAAA (0.54) | KDM4ENAAASMN1; SMN2GPR84HPGD | |
| SCHEMBL6663162 | 0.90 | NPC1 (0.42) | KDM4ENAAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2428932 | 0.83 | NPC1 (0.45) | HTTKDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL22534026 | 0.83 | NPC1 (0.38) | KDM4ENAAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL26529206 | 0.81 | NEK1 (0.46) | HTTKDM4EHPGDNPC1RAB9A | |
| SCHEMBL10336338 | 0.81 | PAOX (0.42) | KDM4ENAAA | |
| SCHEMBL22372064 | 0.81 | HPGD (0.44) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL15874865 | 0.80 | PRMT5 (0.37) | SMN1; SMN2NPC1RAB9AHSPA5 | |
| SCHEMBL26528219 | 0.78 | SMN1; SMN2 (0.45) | TSHRKDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350520-A | IMIDAZOLE-2-CARBOXAMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | claimed |
| US-4350520-A | IMIDAZOLE-2-CARBOXAMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |