SCHEMBL22534026

SCHEMBL22534026

CCO[Si](CCCNC(=O)c1ncc[nH]1)(OCC)OCC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
KIF11 P52732 1/20 0.36
HSPA5 P11021 1/20 0.36
HCRTR1 O43613 1/20 0.36
NAMPT P43490 4/20 0.36
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NAAA Q02083 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11260129 0.83 HTT (0.47) NPC1RAB9AHSPA5KDM4ENAAA
SCHEMBL5579468 0.81 NAAA (0.51) KIF11ALDH1A1KDM4ENAAASMN1; SMN2
SCHEMBL8747369 0.80 NAAA (0.54) ALDH1A1KDM4ENAAASMN1; SMN2
SCHEMBL6663162 0.79 NPC1 (0.42) NPC1RAB9AKIF11HSPA5PRMT5
SCHEMBL22372064 0.77 HPGD (0.44) NPC1RAB9AHSPA5ALDH1A1KDM4E
SCHEMBL29771107 0.76 NPC1 (0.34) NPC1RAB9A
SCHEMBL2428932 0.76 NPC1 (0.45) NPC1RAB9AKIF11HSPA5PRMT5
SCHEMBL10336338 0.74 PAOX (0.42) KIF11PRMT5WDR77KDM4ENAAA
SCHEMBL15874865 0.73 PRMT5 (0.37) NPC1RAB9AKIF11HSPA5NAMPT
SCHEMBL8871055 0.73 SMN1; SMN2 (0.47) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119932662-A Circuit board low-profile roughened copper foil and application thereof 中城财宏科技(江苏)有限公司 2025-05-06 CN claimed
CN-116875128-B Release film and preparation method thereof 绍兴翔宇绿色包装有限公司 2024-08-13 CN claimed
CN-116875128-A Release film and preparation method thereof 绍兴翔宇绿色包装有限公司 2023-10-13 CN claimed
US-20220177494-A1 pH-RESPONSIVE SILICA METAL ORGANIC FRAMEWORK NANOPARTICLES FOR DELIVERY OF BIOACTIVE MOLECULES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-06-09 US claimed
WO-2020210367-A1 PH-RESPONSIVE SILICA METAL ORGANIC FRAMEWORK NANOPARTICLES FOR DELIVERY OF BIO ACTIVE MOLECULES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-10-15 WO claimed
CN-119932662-A Circuit board low-profile roughened copper foil and application thereof 中城财宏科技(江苏)有限公司 2025-05-06 CN disclosed
CN-119932662-A Circuit board low-profile roughened copper foil and application thereof 中城财宏科技(江苏)有限公司 2025-05-06 CN disclosed
US-20240327457-A1 LIPOPEPTIDES, NANOPARTICLES AND METHODS OF USE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-10-03 US disclosed
CN-116875128-B Release film and preparation method thereof 绍兴翔宇绿色包装有限公司 2024-08-13 CN disclosed
CN-116875128-A Release film and preparation method thereof 绍兴翔宇绿色包装有限公司 2023-10-13 CN disclosed
US-20230183723-A1 MULTI-FUNCTIONAL GSH-RESPONSIVE SILICA NANOPARTICLES FOR DELIVERY OF BIOMOLECULES INTO PLANT CELLS NATIONAL SCIENCE FOUNDATION 2023-06-15 US disclosed
US-20220177494-A1 pH-RESPONSIVE SILICA METAL ORGANIC FRAMEWORK NANOPARTICLES FOR DELIVERY OF BIOACTIVE MOLECULES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-06-09 US disclosed
US-20220105202-A1 UNIVERSAL MULTI-FUNCTIONAL GSH-RESPONSIVE SILICA NANOPARTICLES FOR DELIVERY OF BIOMOLECULES INTO CELLS NATIONAL SCIENCE FOUNDATION 2022-04-07 US disclosed
WO-2020210367-A1 PH-RESPONSIVE SILICA METAL ORGANIC FRAMEWORK NANOPARTICLES FOR DELIVERY OF BIO ACTIVE MOLECULES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327457-A1 LIPOPEPTIDES, NANOPARTICLES AND METHODS OF USE NLN, NDUFAB1, NQO1 NPC1 62/4885RAB9A 2164/4885KIF11 2055/4885
US-20220105202-A1 UNIVERSAL MULTI-FUNCTIONAL GSH-RESPONSIVE SILICA NANOPARTICLES FOR DELIVERY OF BIOMOLECULES INTO CELLS HNRNPA2B1, HNRNPA1, HNRNPD NPC1 1268/4885RAB9A 2843/4885KIF11 2187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.