Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252643 | 0.93 | TSHR (0.47) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11259774 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11258579 | 0.86 | CYP2C9 (0.44) | ALDH1A1MAPK1CYP19A1LMNATBXAS1 | |
| SCHEMBL11253421 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11273412 | 0.83 | CYP19A1 (0.42) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11259165 | 0.82 | CYP19A1 (0.49) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL11253398 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11267629 | 0.81 | CYP2C9 (0.43) | ALDH1A1MAPK1CYP19A1LMNATBXAS1 | |
| SCHEMBL11259591 | 0.81 | CYP19A1 (0.42) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11264249 | 0.80 | CYP2A6 (0.52) | ALDH1A1TSHRCYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |