Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270698 | 0.95 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP17A1CYP21A2ALDH1A1 | |
| SCHEMBL11259774 | 0.89 | ALDH1A1 (0.44) | CYP19A1CYP11B1ALDH1A1ALOX15MAPK1 | |
| SCHEMBL11261520 | 0.88 | HMOX1 (0.40) | CYP19A1CYP11B1CYP17A1CYP21A2ALDH1A1 | |
| SCHEMBL11262690 | 0.86 | ADRA2C (0.44) | CYP19A1CYP11B1CYP17A1CYP21A2CYP1A2 | |
| SCHEMBL11254722 | 0.84 | HMOX1 (0.39) | CYP19A1CYP11B1CYP17A1CYP21A2ALDH1A1 | |
| SCHEMBL11273412 | 0.83 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP17A1CYP21A2ALDH1A1 | |
| SCHEMBL11261573 | 0.82 | CYP1A2 (0.49) | CYP19A1CYP11B1CYP11B2POLBCYP1A2 | |
| SCHEMBL11257665 | 0.81 | HMOX1 (0.39) | CYP19A1CYP11B1CYP17A1CYP21A2ALDH1A1 | |
| SCHEMBL11260271 | 0.81 | ALDH1A1 (0.45) | CYP19A1CYP11B1ALDH1A1ALOX15MAPK1 | |
| SCHEMBL10247468 | 0.80 | HMOX1 (0.56) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |