SCHEMBL11260337

SCHEMBL11260337

CC(Oc1ccc(N(C)c2cnc3cc(Br)ccc3n2)cc1)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
CYP2C19 P33261 1/20 0.38
TP53 P04637 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 2/20 0.37
CYP3A4 P08684 1/20 0.37
ALOX15 P16050 1/20 0.37
NFKB1 P19838 1/20 0.37
HIF1A Q16665 1/20 0.37
GMNN O75496 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
APEX1 P27695 1/20 0.37
PMP22 Q01453 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11264919 0.87 CYP1A2 (0.51) CYP1A2TDP1GAACYP2C9PKM
SCHEMBL11264161 0.87 SCN9A (0.41) CYP1A2TDP1GAACYP2C9PKM
SCHEMBL11264953 0.85 CYP1A2 (0.43) CYP1A2TDP1GAACYP2C9PKM
SCHEMBL10971032 0.82 ALDH1A1 (0.54) CYP1A2TDP1GAACYP2C9PKM
SCHEMBL11097501 0.82 TDP1 (0.39) CYP1A2TDP1GAACYP2C9PKM
SCHEMBL11263130 0.79 TDP1 (0.36) CYP1A2TDP1GAACYP2C9PKM
SCHEMBL11267584 0.79 CYP1A2 (0.51) CYP1A2CYP2C9CYP2C19TP53SMN1; SMN2
SCHEMBL27259702 0.78 ALDH1A1 (0.60) CYP1A2TDP1GAACYP2C9PKM
SCHEMBL30946287 0.78 ALDH1A1 (0.60) CYP1A2TDP1GAACYP2C9PKM
SCHEMBL30735548 0.78 ALDH1A1 (0.60) CYP1A2TDP1GAACYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358307-A PREFERENTIAL CONTROLLING OF MONOCOTYLEDONS IN CROPS ICI AUSTRALIA LIMITED (AU) 1982-11-09 US claimed
EP-0026622-A2 Quinoxalinylaminophenoxyalkane carboxylic acid derivatives, their preparation, their use as herbicides and intermediates ICI AUSTRALIA LIMITED (AU) 1981-04-08 EP claimed