Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097255 | 0.88 | KMT2A (0.39) | TDP1GAALMNACYSLTR2CYSLTR1 | |
| SCHEMBL11096193 | 0.87 | CYP1A2 (0.42) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL11122608 | 0.85 | PPARA (0.46) | LMNALDHAPPARAPPARGPABPC1 | |
| SCHEMBL11260337 | 0.82 | CYP1A2 (0.38) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL11280273 | 0.81 | TDP1 (0.35) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL11263130 | 0.80 | TDP1 (0.36) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL11093399 | 0.77 | PPARG (0.42) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL11122607 | 0.77 | PPARA (0.39) | LMNAPPARAPPARGPABPC1CYSLTR2 | |
| SCHEMBL11098428 | 0.77 | MAPT (0.55) | CYP1A2CYP2C9CYP2C19LMNAPPARA | |
| SCHEMBL11097512 | 0.77 | MAPT (0.46) | CYP1A2CYP2C9CYP2C19LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024931-B1 | 1,2,4-BENZOTRIAZINYLAMINOPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1984-10-17 | — | — | EP | claimed |
| US-4310347-A | Herbicidal 1,2,4-benzotriazines | ICI AUSTRALIA LIMITED (AU) | 1982-01-12 | — | — | US | claimed |
| EP-0024931-A2 | 1,2,4-Benzotriazinylaminophenoxyalkane carboxylic acid derivatives, processes for their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-03-11 | — | — | EP | claimed |