⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27974646 | 0.82 | TSHR (0.50) | — | |
| SCHEMBL56468 | 0.79 | — | — | |
| SCHEMBL27974431 | 0.76 | HTT (0.50) | — | |
| SCHEMBL167355 | 0.73 | TSHR (0.70) | — | |
| SCHEMBL7600300 | 0.71 | ALDH1A1 (0.47) | — | |
| SCHEMBL16908593 | 0.70 | — | — | |
| SCHEMBL25851058 | 0.70 | ALDH1A1 (0.41) | — | |
| SCHEMBL19717694 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL5676975 | 0.70 | — | — | |
| SCHEMBL8728537 | 0.69 | HCAR2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580403-B2 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2017-02-28 | — | — | US | claimed |
| US-9255081-B1 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2016-02-09 | — | — | US | claimed |
| US-20160031848-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC | 2016-02-04 | — | — | US | claimed |
| US-10035786-B2 | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180030029-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2018-02-01 | — | — | US | disclosed |
| US-9840490-B2 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2017-12-12 | — | — | US | disclosed |
| EP-3174856-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | Dow AgroSciences LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| US-20170101393-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2017-04-13 | — | — | US | disclosed |
| US-9580403-B2 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160152593-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2016-06-02 | — | — | US | disclosed |
| US-9255081-B1 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2016-02-09 | — | — | US | disclosed |
| WO-2016018442-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2016-02-04 | — | — | WO | disclosed |
| US-20160031848-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC | 2016-02-04 | — | — | US | disclosed |
| US-9029555-B1 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2015-05-12 | — | — | US | disclosed |
| US-4319024-A | ALKYLATION | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |