Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670479 | 0.90 | LMNA (0.38) | HCAR2ALDH1A1TSHRLMNAESR1 | |
| SCHEMBL8724744 | 0.85 | — | — | |
| SCHEMBL9178365 | 0.81 | ALDH1A1 (0.52) | HCAR2ALDH1A1TSHRLMNAESR1 | |
| SCHEMBL31321581 | 0.79 | HCAR2 (0.34) | HCAR2TSHRHPGD | |
| SCHEMBL891844 | 0.78 | — | — | |
| SCHEMBL332824 | 0.78 | — | — | |
| SCHEMBL9844237 | 0.78 | — | — | |
| SCHEMBL28076190 | 0.78 | — | — | |
| SCHEMBL3266107 | 0.77 | ALDH1A1 (0.48) | HCAR2ALDH1A1TSHRLMNAESR1 | |
| SCHEMBL891996 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| US-5455361-A | Process for preparing ketene acetals | WACKER-CHEMIE GMBH (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0589359-B1 | Process for the production of ketene acetals | WACKER CHEMIE GMBH (DE) | 1995-06-28 | — | — | EP | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0589359-A1 | Process for the production of ketene acetals | Wacker-Chemie GmbH (DE) | 1994-03-30 | — | — | EP | disclosed |