Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862392 | 1.00 | APLNR (0.35) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL359379 | 1.00 | APLNR (0.35) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL9909003 | 1.00 | APLNR (0.35) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL9862146 | 1.00 | APLNR (0.35) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11138045 | 0.97 | APLNR (0.33) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11136901 | 0.97 | APLNR (0.33) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL11260869 | 0.88 | APLNR (0.41) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL5246594 | 0.88 | APLNR (0.41) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL3385056 | 0.88 | APLNR (0.41) | APLNRSLC9A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL11802322 | 0.79 | APLNR (0.32) | APLNRKDM4ECYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004822-A | Isomers of 3-acetyl-2,2-dimethyl cyclopropane carboxylic acid derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-04-02 | — | — | US | disclosed |
| US-4622337-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-11 | — | — | US | disclosed |
| US-4464391-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-07 | — | — | US | disclosed |