Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | SDCBP | O00560 | 2/20 | 0.42 |
| ▸ | SDC2 | P34741 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275306 | 1.00 | SLC6A4 (0.47) | SLC6A4HPGDMAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11263911 | 0.98 | SLC6A4 (0.46) | SLC6A4HPGDMAPTALDH1A1SMN1; SMN2 | |
| Fumaric Acid SCHEMBL11269540 | 0.86 | SDCBP (0.46) | HPGDMAPTALDH1A1SMN1; SMN2HTT | |
| Fumaric Acid SCHEMBL11130141 | 0.86 | SDCBP (0.46) | HPGDMAPTALDH1A1SMN1; SMN2HTT | |
| Fumaric Acid SCHEMBL11130146 | 0.86 | SDCBP (0.46) | HPGDMAPTALDH1A1SMN1; SMN2HTT | |
| Fumaric Acid SCHEMBL11261365 | 0.86 | SDCBP (0.46) | HPGDMAPTALDH1A1SMN1; SMN2HTT | |
| Fumaric Acid SCHEMBL11261354 | 0.86 | SDCBP (0.46) | HPGDMAPTALDH1A1SMN1; SMN2HTT | |
| Fumaric Acid SCHEMBL11269551 | 0.86 | SDCBP (0.46) | HPGDMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11267546 | 0.81 | MAOA (0.61) | SLC6A4SMN1; SMN2SDCBPSDC2NPC1 | |
| SCHEMBL11263363 | 0.81 | SLC6A4 (0.47) | SLC6A4MAPTALDH1A1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053015-A1 | 1-Phenylthio-2-aminopropane derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | claimed |
| EP-0053015-A1 | 1-Phenylthio-2-aminopropane derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |