Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595338 | 0.76 | MAPT (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL12431439 | 0.74 | TSHR (0.38) | MAPTMAPK1NPC1TSHRRAB9A | |
| SCHEMBL2866038 | 0.71 | MAPK1 (0.35) | MAPTMAPK1NPC1TSHRRAB9A | |
| SCHEMBL1535989 | 0.69 | MAPK1 (0.34) | MAPTMAPK1NPC1TSHRRAB9A | |
| SCHEMBL1535991 | 0.69 | MAPK1 (0.34) | MAPTMAPK1NPC1TSHRRAB9A | |
| SCHEMBL5535228 | 0.69 | TSHR (0.38) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL13725736 | 0.69 | TSHR (0.38) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL13725734 | 0.69 | TSHR (0.38) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL16850497 | 0.69 | MAPK1 (0.34) | MAPK1NPC1TSHRRAB9AHSD17B10 | |
| SCHEMBL8325213 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331678-A | Carbamoyl pyrazole compounds and their pesticidal application | FBC LIMITED (GB) | 1982-05-25 | — | — | US | disclosed |
| EP-0014810-A2 | Pesticidal pyrazoles, their production, compositions and uses, as well as intermediates and their preparation | FBC LIMITED (GB) | 1980-09-03 | — | — | EP | disclosed |