Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027469 | 0.89 | MAPT (0.50) | MAPTL3MBTL1ALDH1A1HPGDPOLB | |
| SCHEMBL3737958 | 0.79 | NR1I2 (0.60) | L3MBTL1POLBMAPK1LMNANR1I2 | |
| SCHEMBL2392373 | 0.79 | POLB (0.42) | MAPTL3MBTL1ALDH1A1HPGDPOLB | |
| SCHEMBL17365878 | 0.79 | ACHE (0.59) | MAPTL3MBTL1ALDH1A1HPGDPOLB | |
| SCHEMBL11011178 | 0.79 | SYK (0.49) | MAPTL3MBTL1ALDH1A1HPGDPOLB | |
| SCHEMBL13077263 | 0.79 | ACHE (0.59) | MAPTL3MBTL1ALDH1A1HPGDPOLB | |
| SCHEMBL6941203 | 0.77 | MAPT (0.61) | MAPTL3MBTL1ALDH1A1HPGDPOLB | |
| SCHEMBL25484238 | 0.76 | ALDH1A1 (0.50) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11541940 | 0.76 | POLB (0.40) | MAPTL3MBTL1ALDH1A1HPGDPOLB | |
| SCHEMBL11253301 | 0.76 | ALDH1A1 (0.42) | MAPTL3MBTL1ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343809-A | ANTIANEMIA | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |