Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16737185 | 0.85 | HCAR3 (0.53) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5659639 | 0.81 | HCAR3 (0.44) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL1344661 | 0.81 | HCAR3 (0.58) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8812743 | 0.80 | HCAR3 (0.51) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3673595 | 0.79 | TDP1 (0.48) | MAPTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8088325 | 0.79 | MAPT (0.44) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL2946229 | 0.77 | CHRM2 (0.65) | HCAR3MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11900601 | 0.77 | MAPT (0.42) | HCAR3MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3666821 | 0.76 | GPR35 (0.48) | MAPTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11273856 | 0.76 | MEN1 (0.51) | HCAR3MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328369-A | Process for the production of 2,6-dinitro-N-alkyl-anilines | RUMIANCA S.P.A. (IT) | 1982-05-04 | — | — | US | claimed |
| US-4328369-A | Process for the production of 2,6-dinitro-N-alkyl-anilines | RUMIANCA S.P.A. (IT) | 1982-05-04 | — | — | US | disclosed |
| US-4328369-A | Process for the production of 2,6-dinitro-N-alkyl-anilines | RUMIANCA S.P.A. (IT) | 1982-05-04 | — | — | US | disclosed |
| US-4328369-A | Process for the production of 2,6-dinitro-N-alkyl-anilines | RUMIANCA S.P.A. (IT) | 1982-05-04 | — | — | US | disclosed |
| US-3927127-A | Nitration process | RHONE POULENC NEDERLANDS B.V. (NL) | 1975-12-16 | — | — | US | disclosed |