Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13480553 | 0.92 | TAS1R3 (0.60) | CYP1A2TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL11139025 | 0.86 | CYP1A2 (0.56) | CYP1A2TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL13754118 | 0.80 | KDM4E (0.61) | CYP1A2TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL10458447 | 0.78 | KDM4E (0.72) | CYP1A2RAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL23069069 | 0.78 | MEN1 (0.76) | CYP1A2RAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL13296460 | 0.76 | POLB (0.70) | TAS1R3TAS1R1RAB9ANPC1CASR | |
| SCHEMBL10400585 | 0.76 | EPHX1 (0.57) | RAB9ANPC1SMN1; SMN2KMT2AHTT | |
| SCHEMBL8830517 | 0.75 | SMN1; SMN2 (0.73) | CYP1A2TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL14690405 | 0.75 | KMT2A (0.58) | CYP1A2TAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL27714794 | 0.75 | MAPK1 (0.61) | CYP1A2TAS1R3TAS1R1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350700-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1982-09-21 | — | — | US | disclosed |
| US-4287207-A | USED AS AN ANALGESIC, ANTIPYRETIC OR ANTIINFLAMMATORY AGENT | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-09-01 | — | — | US | disclosed |