Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | CASP3 | P42574 | 2/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700678 | 0.90 | MEN1 (0.87) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL11449284 | 0.89 | CYP1A2 (0.65) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL11006185 | 0.88 | NPC1 (0.78) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL6260101 | 0.88 | MEN1 (0.68) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL8830517 | 0.87 | SMN1; SMN2 (0.73) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL8421117 | 0.87 | CYP1A2 (0.62) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL9036644 | 0.87 | CYP1A2 (0.68) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL24449161 | 0.87 | CYP1A2 (0.77) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL21858368 | 0.87 | ALDH1A1 (0.70) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL7675947 | 0.87 | GRIK1 (0.74) | KDM4ECYP1A2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387824-A2 | Thermoplastic molding masses on the basis of impact modified polyamide and functionalised polyphenylenether | BASF Aktiengesellschaft (DE) | 1990-09-19 | — | — | EP | disclosed |
| EP-0382167-A1 | Process for preparation of compatible mixtures of N-aryl polyglutarimides with styrene copolymers | ENICHEM S.p.A. (IT) | 1990-08-16 | — | — | EP | disclosed |