Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263613 | 0.88 | CYP3A4 (0.41) | CYP3A4ALDH1A1MAPTTDP1TP53 | |
| SCHEMBL11266522 | 0.87 | HMOX1 (0.54) | HMOX1 | |
| SCHEMBL11273007 | 0.87 | CYP1A2 (0.42) | CYP3A4MAPTCYP1A2CYP19A1HMOX1 | |
| SCHEMBL11270574 | 0.87 | CYP3A4 (0.47) | CYP3A4ALDH1A1MAPTTDP1TP53 | |
| SCHEMBL11260759 | 0.86 | HMOX1 (0.44) | CYP3A4ALDH1A1MAPTTDP1TP53 | |
| SCHEMBL11260782 | 0.85 | KDM4E (0.46) | ALDH1A1HMOX1 | |
| SCHEMBL11262523 | 0.85 | CYP3A4 (0.45) | CYP3A4ALDH1A1MAPTTDP1TP53 | |
| SCHEMBL11258234 | 0.83 | MEN1 (0.45) | CYP3A4ALDH1A1MAPTTDP1TP53 | |
| SCHEMBL11261172 | 0.83 | HMOX1 (0.40) | HMOX1 | |
| SCHEMBL11252503 | 0.82 | CYP3A4 (0.41) | CYP3A4ALDH1A1MAPTTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |