Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262523 | 0.95 | CYP3A4 (0.45) | CYP3A4MAPTTDP1MEN1KMT2A | |
| SCHEMBL11254606 | 0.93 | CYP3A4 (0.50) | CYP3A4MAPTTDP1MEN1KMT2A | |
| SCHEMBL11266898 | 0.89 | CYP3A4 (0.49) | CYP3A4MAPTTDP1MEN1KMT2A | |
| SCHEMBL11259195 | 0.89 | CYP3A4 (0.48) | CYP3A4MAPTTDP1MEN1KMT2A | |
| SCHEMBL11257564 | 0.88 | KDM4E (0.50) | ALDH1A1HMOX1LMNA | |
| SCHEMBL11266913 | 0.88 | HMOX1 (0.42) | CYP3A4MAPTTDP1MEN1KMT2A | |
| SCHEMBL11258574 | 0.88 | CYP19A1 (0.48) | CYP3A4MAPTTDP1MEN1KMT2A | |
| SCHEMBL11261572 | 0.87 | CYP3A4 (0.42) | CYP3A4MAPTTDP1MEN1KMT2A | |
| SCHEMBL11265311 | 0.86 | HMOX1 (0.47) | HMOX1 | |
| SCHEMBL10247104 | 0.86 | CYP19A1 (0.51) | CYP19A1HMOX1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | claimed |
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |