Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 9/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 9/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 9/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 9/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 8/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262288 | 0.88 | CACNA1F (0.50) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL11267928 | 0.86 | NR3C2 (0.43) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL11392503 | 0.81 | CACNA1B (0.53) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL11261753 | 0.81 | HIF1A (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL11386854 | 0.80 | CACNA1B (0.50) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL11262343 | 0.79 | CACNA1B (0.51) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL3026966 | 0.78 | ABCC1 (0.71) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11389848 | 0.77 | CACNA1B (0.50) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL11260210 | 0.76 | CACNA1F (0.66) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11386624 | 0.76 | CACNA1B (0.46) | CACNA1FCACNA1DCACNA1SCACNA1CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |