Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 10/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261733 | 0.86 | CACNA1F (0.50) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11330289 | 0.86 | CACNA1B (0.35) | NR3C2CACNA1BCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11262288 | 0.78 | CACNA1F (0.50) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3018702 | 0.77 | NR3C2 (0.61) | NR3C2CACNA1B | |
| SCHEMBL11261753 | 0.77 | HIF1A (0.44) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11263102 | 0.75 | NR3C2 (0.66) | NR3C2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11267599 | 0.74 | CCR1 (0.41) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11262343 | 0.72 | CACNA1B (0.51) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11392503 | 0.71 | CACNA1B (0.53) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11386854 | 0.70 | CACNA1B (0.50) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |