Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262288 | 0.81 | CACNA1F (0.50) | HIF1ACYP2C9MEN1CYP1A2CYP3A4 | |
| SCHEMBL11261733 | 0.81 | CACNA1F (0.50) | ADORA3CACNA1BCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11386854 | 0.79 | CACNA1B (0.50) | HIF1ACYP2C9MEN1CYP1A2CYP3A4 | |
| SCHEMBL11253160 | 0.78 | MAPT (0.55) | HIF1ACYP2C9MEN1CYP1A2CYP3A4 | |
| SCHEMBL11267928 | 0.77 | NR3C2 (0.43) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11256475 | 0.77 | SLC6A3 (0.47) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL11254571 | 0.77 | CACNA1B (0.47) | POLBADORA3CACNA1BCACNA1FCACNA1D | |
| SCHEMBL11267599 | 0.75 | CCR1 (0.41) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9502243 | 0.75 | ADORA3 (0.73) | HIF1ACYP2C9MEN1CYP1A2CYP3A4 | |
| SCHEMBL11392503 | 0.74 | CACNA1B (0.53) | ADORA3CACNA1BCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |