Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431592 | 0.88 | KMT2A (0.68) | KMT2AMEN1ESR1ESR2PKM | |
| SCHEMBL11267816 | 0.84 | KMT2A (0.58) | KMT2AMEN1ESR1ESR2KDM4E | |
| SCHEMBL10457215 | 0.83 | KMT2A (0.66) | KMT2AMEN1ESR1ESR2PKM | |
| SCHEMBL14645914 | 0.82 | KMT2A (0.61) | KMT2AMEN1ESR1ESR2PKM | |
| SCHEMBL18460967 | 0.81 | KDM4E (0.70) | KMT2AMEN1ESR1ESR2PKM | |
| SCHEMBL11264577 | 0.81 | SLC6A3 (0.53) | KMT2AESR1ESR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL1697526 | 0.80 | GPR52 (0.50) | KDM4ELMNAHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL29883975 | 0.80 | GPR52 (0.50) | KDM4ELMNAHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL11268952 | 0.80 | SLC6A3 (0.63) | KMT2AMEN1ESR1ESR2KDM4E | |
| SCHEMBL28731362 | 0.80 | KMT2A (0.67) | KMT2AMEN1ESR1ESR2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338323-A | Piperidylbenzimidazolinone derivatives | SCIENCE UNION ET CIE (FR) | 1982-07-06 | — | — | US | disclosed |